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Cagrilintide can also reduce the expression of tartrate-resistant acid phosphatase (TRAP), a marker of osteoclast activity and bone resorption (Cornish et al., 2015, Bonekey Rep.)

In ALT non-responders, glutathione treatment reduced triglyceride levels but increased FBS levels

On the other hand, overexpression of HO-1 can lead to excessive free iron release, promoting Fenton reactions and potentially exacerbating ferroptosis under specific conditions (128)