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Treatment response evaluation should focus on objective measures relevant to the specific indication being treated

[1] This abnormal keratinization and skin cell proliferation combined with down-regulating 5-Reductase (due to insufficient IGF-1) [19] eventually atrophies the sebaceous glands by reducing sebocyte proliferation that would typically be induced by DHT, if not for the loss of 5-Reductase regulation from IGF-1

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