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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Playford D.A., Watts G.F., Croft K.D., Burke V

The drug, or vaccine, needs to find a metabolic system in humans that generates a certain metabolic intermediate, which generally accumulates in excess, in the same patient, where this metabolite stimulates the proliferation of the monocytic-macrophage system, which leads to the activation of latent viruses incorporated into the host DNA

In fact, this extract was more effective than the common antibiotic kanamycin, the presumed mechanism being disruption of microbial membranes by phenolic compounds

IGF-1R in cancer therapeutics Not surprisingly, the IGF-1R signaling pathway has attracted intense interest from the drug development community