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At clinical doses, the peptide activates collagen synthesis, accelerates cell turnover, and modulates the inflammatory response across multiple tissue types

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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment

In addition, supplementation with ursodeoxycholic acid (UDCA) elicited a reduced body weight gain similar to that by CA supplementation