Quintana-Cabrera R, Quirin C, Glytsou C, Corrado M, Urbani A, Pellattiero A, et al
Despite their potential to ameliorate neurodegeneration through upregulation of NRF2 and its target genes, as shown by numerous pre-clinical studies, their molecular off-target effects and concomitant unpredictable side-effects pose an obstacle for clinical trials and approval
Targeting apoptosis-related mechanisms may effectively delay ovarian reserve decline, offering a viable approach to fertility preservation and reproductive health management
For procedures in which complications are catastrophic, including TJA, counseling should prioritize discontinuation of nonessential injectable biologics before surgery, explicit documentation of exposure, and heightened vigilance for early wound complications