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5.4 Advanced strategies for enhanced transepithelial transport using CPPs For physical mixing methods, the extent of intermolecular interaction between CPP and cargo is a key determinant for efficient delivery, as shown for penetratin and its analogs (Zhu et al., 2014)

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The peptide appears to recognize tissue states and adjust its effects accordingly, promoting healing without causing the excessive NO production that damages tissue

Together, they create an optimal healing environment that reduces recovery time by 30-50% compared to natural healing in many reported cases