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It has a complicated pathogenesis associated with environmental modifications, genetic predispositions, deregulated dopamine metabolism, neuroinflammation, oxidative stress, and mitochondrial dysfunction (Gke okal et al., 2017

Anatomy & Pathophysiology The Pancreas and Insulin Regulation: The islets of Langerhans in the pancreatic parenchyma contain beta cells (insulin-secreting), alpha cells (glucagon-secreting), and delta cells (somatostatin-secreting)

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[PubMed] [Google Scholar] 79.Ilic S., Drmic D., Franjic S., Kolenc D., Coric M., Brcic L., Klicek R., Radic B., Sever M., Djuzel V., et al