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The peak at 1580 cm -1 was attributed to the aromatic C-H bending vibration and the peak at 1403 cm -1 was related to C-H bending vibration 49

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Elevating the head of the bed 6 to 8 inches provides overnight gravitational protection

Clinical studies and meta-analyses have demonstrated that daily folic acid supplementation (typically 5 mg or more) significantly reduces the incidence of gastrointestinal side effects, elevations in serum transaminase (liver enzyme) levels, and the overall rate of patients discontinuing methotrexate therapy for any reason (Friedman & Cronstein, 2019)