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Levels of this peptide decline significantly with age, which may contribute to slower healing, reduced collagen production, and visible skin aging

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The weight loss achieved by CagriSema (-20.4% at 68 weeks) is comparable to that reported with the dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist tirzepatide (-20.9% with the 15-mg dose at 72 weeks in SURMOUNT-1) [14]

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