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For example, the Lactobacillus rhamnosus GG strain may modulate intestinal immune cells to reduce the release of inflammatory cytokines ( 4.3 The role of B vitamins and vitamin D In children with ASD, abnormalities in methylation metabolism have been widely documented, including a decreased S-adenosylmethionine to S-adenosylhomocysteine (SAM/SAH) ratio and elevated homocysteine levels (Wilson et al., 2021)

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